{"type":"video","version":"1.0","html":"<iframe src=\"https://www.loom.com/embed/3b2c9a52e0c5473fbd6e8ebbdd496646\" frameborder=\"0\" width=\"1920\" height=\"1440\" webkitallowfullscreen mozallowfullscreen allowfullscreen></iframe>","height":1440,"width":1920,"provider_name":"Loom","provider_url":"https://www.loom.com","thumbnail_height":1440,"thumbnail_width":1920,"thumbnail_url":"https://cdn.loom.com/sessions/thumbnails/3b2c9a52e0c5473fbd6e8ebbdd496646-88723e88d0abfb6a.gif","duration":258.219,"title":"Static Docking and Flexible Docking Review","description":"In this video, I walk you through the Binding Chemistry Virtual Screening Engine, focusing on rigid receptor docking, flexible docking, and ensemble docking, each serving different stages of our screening process. I demonstrate how to set up a docking campaign using demo files, specifically targeting AXL with 800 compounds. I emphasize the importance of understanding structure-activity relationships and identifying key residues for flexible docking. I also highlight the use of convolutional neural network rescoring for better pose positioning. Please follow the steps outlined to run your own docking campaigns effectively."}