{"type":"video","version":"1.0","html":"<iframe src=\"https://www.loom.com/embed/ded49950d53b4b0cb9a3d6fccc13b724\" frameborder=\"0\" width=\"1754\" height=\"1315\" webkitallowfullscreen mozallowfullscreen allowfullscreen></iframe>","height":1315,"width":1754,"provider_name":"Loom","provider_url":"https://www.loom.com","thumbnail_height":1315,"thumbnail_width":1754,"thumbnail_url":"https://cdn.loom.com/sessions/thumbnails/ded49950d53b4b0cb9a3d6fccc13b724-4a25176b919124c5.gif","duration":123.563,"title":"Mechanome Predicts Viral Entry Membrane Forces","description":"This Loom presents Meccanome, an open source tool that predicts membrane mechanics and protein players involved in membrane bending during viral entry. Using structure or shape data, it predicts bending proteins and actin, and with sufficient data it can estimate the actual forces involved. It identifies that influenza viruses require a curvature driver that wedges into the bilayer, and argues that successful entry depends on coactivity of membrane-bending proteins and actin. The speaker also mentions connecting Meccanome to Claude to enable hypothesis testing."}