video1.0<iframe src="https://www.loom.com/embed/b2e7d39a09d74e7c88b67147778a8c8a" frameborder="0" width="1920" height="1440" webkitallowfullscreen mozallowfullscreen allowfullscreen></iframe>14401920Loomhttps://www.loom.com14401920https://cdn.loom.com/sessions/thumbnails/b2e7d39a09d74e7c88b67147778a8c8a-f2dd060a3f0e42e8.gif2361.2In this presentation, I discussed the challenges of treating Lyme disease, particularly the persistence of the Borrelia spirochetes after conventional antibiotic treatment. It’s estimated that over 2 million people in the U.S. suffer from post-treatment Lyme disease, characterized by symptoms like pain, cognitive impairment, and fatigue. I highlighted the importance of distinguishing antibiotic tolerance from resistance and shared findings from animal models and human autopsy specimens that indicate spirochetes can remain viable but non-culturable after treatment. I believe that exploring combination therapy could be a promising direction for more effective treatment, and I encourage further research in this area. Thank you for your attention, and I look forward to any questions you may have.